All position ranks are: QB RB WR TE FLEX DEF
These rankings were updated as of Sat 10:01 AM ET.
| Rank | Player | Match |
| 1 | Christian McCaffrey | SF vs Chi |
| 2 | Puka Nacua | LAR @ Atl |
| 3 | Bijan Robinson | Atl vs LAR |
| 4 | De'Von Achane | Mia vs TB |
| 5 | Ja'Marr Chase | Cin vs Ari |
| 6 | Jaxon Smith-Njigba | Sea @ Car |
| 7 | Jonathan Taylor | Ind vs Jax |
| 8 | Ashton Jeanty | LV vs NYG |
| 9 | James Cook | Buf vs Phi |
| 10 | Saquon Barkley | Phi @ Buf |
| 11 | Trey McBride | Ari @ Cin |
| 12 | Chase Brown | Cin vs Ari |
| 13 | Travis Etienne | Jax @ Ind |
| 14 | Drake London | Atl vs LAR |
| 15 | Kyren Williams | LAR @ Atl |
| 16 | Bucky Irving | TB @ Mia |
| 17 | Chris Olave | NO @ Ten |
| 18 | Mike Evans | TB @ Mia |
| 19 | Breece Hall | NYJ vs NE |
| 20 | Tee Higgins | Cin vs Ari |
| 21 | Tyrone Tracy Jr. | NYG @ LV |
| 22 | Jaylen Warren | Pit @ Cle |
| 23 | Rico Dowdle | Car vs Sea |
| 24 | Kenneth Walker III | Sea @ Car |
| 25 | D'Andre Swift | Chi @ SF |
| 26 | Rhamondre Stevenson | NE @ NYJ |
| 27 | Marvin Harrison Jr. | Ari @ Cin |
| 28 | Kenneth Gainwell | Pit @ Cle |
| 29 | Jauan Jennings | SF vs Chi |
| 30 | Michael Carter | Ari @ Cin |
| 31 | Stefon Diggs | NE @ NYJ |
| 32 | Jakobi Meyers | Jax @ Ind |
| 33 | DJ Moore | Chi @ SF |
| 34 | Michael Wilson | Ari @ Cin |
| 35 | A.J. Brown | Phi @ Buf |
| Rank | Player | Match |
| 36 | TreVeyon Henderson | NE @ NYJ |
| 37 | Emeka Egbuka | TB @ Mia |
| 38 | Tony Pollard | Ten vs NO |
| 39 | Tetairoa McMillan | Car vs Sea |
| 40 | Jaylen Waddle | Mia vs TB |
| 41 | Wan'Dale Robinson | NYG @ LV |
| 42 | Kyle Pitts | Atl vs LAR |
| 43 | Hunter Henry | NE @ NYJ |
| 44 | Brian Thomas Jr. | Jax @ Ind |
| 45 | Michael Pittman Jr. | Ind vs Jax |
| 46 | Mack Hollins | NE @ NYJ |
| 47 | Juwan Johnson | NO @ Ten |
| 48 | Zach Charbonnet | Sea @ Car |
| 49 | Parker Washington | Jax @ Ind |
| 50 | DeVonta Smith | Phi @ Buf |
| 51 | Tre Tucker | LV vs NYG |
| 52 | Kyle Monangai | Chi @ SF |
| 53 | George Kittle | SF vs Chi |
| 54 | Harold Fannin Jr. | Cle vs Pit |
| 55 | Brenton Strange | Jax @ Ind |
| 56 | Chris Godwin | TB @ Mia |
| 57 | Tyjae Spears | Ten vs NO |
| 58 | Colston Loveland | Chi @ SF |
| 59 | Raheim Sanders | Cle vs Pit |
| 60 | Chuba Hubbard | Car vs Sea |
| 61 | Alec Pierce | Ind vs Jax |
| 62 | Blake Corum | LAR @ Atl |
| 63 | Dallas Goedert | Phi @ Buf |
| 64 | Rashid Shaheed | Sea @ Car |
| 65 | Tyler Warren | Ind vs Jax |
| 66 | Josh Downs | Ind vs Jax |
| 67 | Colby Parkinson | LAR @ Atl |
| 68 | Darren Waller | Mia vs TB |
| 69 | Theo Johnson | NYG @ LV |
| 70 | AJ Barner | Sea @ Car |
