All position ranks are: QB RB WR TE FLEX DEF
These rankings were updated as of Sat 10:00 AM ET.
| Rank | Player | Match |
| 1 | Christian McCaffrey | SF vs Chi |
| 2 | Bijan Robinson | Atl vs LAR |
| 3 | De'Von Achane | Mia vs TB |
| 4 | Jonathan Taylor | Ind vs Jax |
| 5 | Ashton Jeanty | LV vs NYG |
| 6 | James Cook | Buf vs Phi |
| 7 | Saquon Barkley | Phi @ Buf |
| 8 | Chase Brown | Cin vs Ari |
| 9 | Travis Etienne | Jax @ Ind |
| 10 | Kyren Williams | LAR @ Atl |
| 11 | Bucky Irving | TB @ Mia |
| 12 | Breece Hall | NYJ vs NE |
| 13 | Tyrone Tracy Jr. | NYG @ LV |
| 14 | Jaylen Warren | Pit @ Cle |
| 15 | Rico Dowdle | Car vs Sea |
| 16 | Kenneth Walker III | Sea @ Car |
| 17 | D'Andre Swift | Chi @ SF |
| 18 | Rhamondre Stevenson | NE @ NYJ |
| 19 | Kenneth Gainwell | Pit @ Cle |
| 20 | Michael Carter | Ari @ Cin |
| Rank | Player | Match |
| 21 | TreVeyon Henderson | NE @ NYJ |
| 22 | Tony Pollard | Ten vs NO |
| 23 | Zach Charbonnet | Sea @ Car |
| 24 | Kyle Monangai | Chi @ SF |
| 25 | Tyjae Spears | Ten vs NO |
| 26 | Raheim Sanders | Cle vs Pit |
| 27 | Chuba Hubbard | Car vs Sea |
| 28 | Blake Corum | LAR @ Atl |
| 29 | Samaje Perine | Cin vs Ari |
| 30 | Devin Singletary | NYG @ LV |
| 31 | Audric Estime | NO @ Ten |
| 32 | Emari Demercado | Ari @ Cin |
| 33 | Trayveon Williams | Cle vs Pit |
| 34 | Tyler Allgeier | Atl vs LAR |
| 35 | Evan Hull | NO @ Ten |
| 36 | Rachaad White | TB @ Mia |
| 37 | Dylan Sampson | Cle vs Pit |
| 38 | Raheem Mostert | LV vs NYG |
| 39 | Brian Robinson | SF vs Chi |
| 40 | Isaiah Davis | NYJ vs NE |
