All position ranks are: QB RB WR TE FLEX DEF
These rankings were updated as of Wed 1:36 PM ET.
| Rank | Player | Match |
| 1 | Jaxon Smith-Njigba | Sea vs Min |
| 2 | Amon-Ra St. Brown | Det vs GB |
| 3 | Puka Nacua | LAR @ Car |
| 4 | Ja'Marr Chase | Cin @ Bal |
| 5 | Rashee Rice | KC @ Dal |
| 6 | CeeDee Lamb | Dal vs KC |
| 7 | Davante Adams | LAR @ Car |
| 8 | George Pickens (Q) | Dal vs KC |
| 9 | Emeka Egbuka | TB vs Ari |
| 10 | Zay Flowers | Bal vs Cin |
| 11 | A.J. Brown | Phi vs Chi |
| 12 | Nico Collins | Hou @ Ind |
| 13 | Chris Olave | NO @ Mia |
| 14 | DeVonta Smith (Q) | Phi vs Chi |
| 15 | Ladd McConkey | LAC vs LV |
| 16 | Justin Jefferson | Min @ Sea |
| 17 | Jaylen Waddle | Mia vs NO |
| 18 | Tetairoa McMillan | Car vs LAR |
| 19 | Stefon Diggs | NE vs NYG |
| 20 | Courtland Sutton | Den @ Wsh |
| 21 | Jameson Williams | Det vs GB |
| 22 | Troy Franklin | Den @ Wsh |
| 23 | Wan'Dale Robinson | NYG @ NE |
| 24 | D.K. Metcalf (Q) | Pit vs Buf |
| 25 | Michael Pittman Jr. | Ind vs Hou |
| Rank | Player | Match |
| 26 | Quentin Johnston | LAC vs LV |
| 27 | Romeo Doubs | GB @ Det |
| 28 | Jakobi Meyers | Jax @ Ten |
| 29 | Xavier Worthy | KC @ Dal |
| 30 | Khalil Shakir | Buf @ Pit |
| 31 | Michael Wilson | Ari @ TB |
| 32 | Rome Odunze | Chi @ Phi |
| 33 | Jordan Addison | Min @ Sea |
| 34 | Keenan Allen | LAC vs LV |
| 35 | Parker Washington | Jax @ Ten |
| 36 | Deebo Samuel | Wsh vs Den |
| 37 | Jauan Jennings | SF @ Cle |
| 38 | Alec Pierce | Ind vs Hou |
| 39 | Christian Watson | GB @ Det |
| 40 | Terry McLaurin (Q) | Wsh vs Den |
| 41 | Tre Tucker | LV @ LAC |
| 42 | Kayshon Boutte | NE vs NYG |
| 43 | Chris Godwin | TB vs Ari |
| 44 | DJ Moore | Chi @ Phi |
| 45 | Drake London (D) | Atl @ NYJ |
| 46 | Chimere Dike | Ten vs Jax |
| 47 | Cooper Kupp | Sea vs Min |
| 48 | Jayden Higgins | Hou @ Ind |
| 49 | Jerry Jeudy | Cle vs SF |
| 50 | Brian Thomas Jr. (Q) | Jax @ Ten |
