All position ranks are: QB RB WR TE FLEX DEF
These rankings were updated as of Thu 12:04 PM ET.
| Rank | Player | Match |
| 1 | Christian McCaffrey | SF @ Ari |
| 2 | De'Von Achane | Mia vs Wsh |
| 3 | Bijan Robinson | Atl vs Car |
| 4 | Josh Jacobs | GB @ NYG |
| 5 | James Cook | Buf vs TB |
| 6 | Puka Nacua | LAR vs Sea |
| 7 | Jahmyr Gibbs | Det @ Phi |
| 8 | Saquon Barkley | Phi vs Det |
| 9 | Ashton Jeanty | LV vs Dal |
| 10 | Ja'Marr Chase | Cin @ Pit |
| 11 | Jaxon Smith-Njigba | Sea @ LAR |
| 12 | TreVeyon Henderson | NE vs NYJ |
| 13 | Trey McBride | Ari vs SF |
| 14 | Rico Dowdle (Q) | Car @ Atl |
| 15 | Drake London (Q) | Atl vs Car |
| 16 | CeeDee Lamb | Dal @ LV |
| 17 | Jaylen Warren | Pit vs Cin |
| 18 | Amon-Ra St. Brown | Det @ Phi |
| 19 | Emeka Egbuka | TB @ Buf |
| 20 | Travis Etienne | Jax vs LAC |
| 21 | Javonte Williams | Dal @ LV |
| 22 | Justin Jefferson | Min vs Chi |
| 23 | Derrick Henry | Bal @ Cle |
| 24 | Kyren Williams | LAR vs Sea |
| 25 | Brock Bowers | LV vs Dal |
| 26 | Chase Brown | Cin @ Pit |
| 27 | Davante Adams (Q) | LAR vs Sea |
| 28 | Breece Hall | NYJ @ NE |
| 29 | George Pickens | Dal @ LV |
| 30 | Zay Flowers | Bal @ Cle |
| 31 | Rashee Rice | KC @ Den |
| 32 | Kimani Vidal | LAC @ Jax |
| 33 | A.J. Brown | Phi vs Det |
| 34 | Ladd McConkey (Q) | LAC @ Jax |
| 35 | Stefon Diggs | NE vs NYJ |
| Rank | Player | Match |
| 36 | Jaylen Waddle | Mia vs Wsh |
| 37 | Nico Collins | Hou @ Ten |
| 38 | Quinshon Judkins | Cle vs Bal |
| 39 | Woody Marks | Hou @ Ten |
| 40 | D.K. Metcalf | Pit vs Cin |
| 41 | Rachaad White | TB @ Buf |
| 42 | D'Andre Swift (Q) | Chi @ Min |
| 43 | DeVonta Smith | Phi vs Det |
| 44 | Deebo Samuel | Wsh @ Mia |
| 45 | George Kittle | SF @ Ari |
| 46 | Tetairoa McMillan | Car @ Atl |
| 47 | Jacory Croskey-Merritt | Wsh @ Mia |
| 48 | Quentin Johnston (Q) | LAC @ Jax |
| 49 | Rome Odunze (Q) | Chi @ Min |
| 50 | RJ Harvey | Den vs KC |
| 51 | Aaron Jones (Q) | Min vs Chi |
| 52 | Kenneth Walker III | Sea @ LAR |
| 53 | Romeo Doubs | GB @ NYG |
| 54 | Khalil Shakir (Q) | Buf vs TB |
| 55 | Tee Higgins | Cin @ Pit |
| 56 | Tre Tucker | LV vs Dal |
| 57 | Tyrone Tracy Jr. | NYG vs GB |
| 58 | Jordan Addison | Min vs Chi |
| 59 | Courtland Sutton | Den vs KC |
| 60 | Cade Otton | TB @ Buf |
| 61 | Hunter Henry | NE vs NYJ |
| 62 | Jameson Williams | Det @ Phi |
| 63 | Wan'Dale Robinson | NYG vs GB |
| 64 | Keenan Allen | LAC @ Jax |
| 65 | Sam LaPorta (Q) | Det @ Phi |
| 66 | Jauan Jennings | SF @ Ari |
| 67 | David Montgomery | Det @ Phi |
| 68 | Dallas Goedert | Phi vs Det |
| 69 | Jakobi Meyers | Jax vs LAC |
| 70 | Kareem Hunt | KC @ Den |
