All position ranks are: QB RB WR TE FLEX DEF
These rankings were updated as of Sat 9:48 AM ET.
| Rank | Player | Match |
| 1 | Saquon Barkley | Phi vs Car |
| 2 | Alvin Kamara | NO @ NYG |
| 3 | Chase Brown | Cin @ Dal |
| 4 | De'Von Achane | Mia vs NYJ |
| 5 | Bijan Robinson | Atl @ Min |
| 6 | Kyren Williams | LAR vs Buf |
| 7 | James Conner | Ari vs Sea |
| 8 | Bucky Irving (Q) | TB vs LV |
| 9 | Kenneth Walker III (Q) | Sea @ Ari |
| 10 | Aaron Jones | Min vs Atl |
| 11 | James Cook | Buf @ LAR |
| 12 | Najee Harris | Pit vs Cle |
| 13 | Tony Pollard | Ten vs Jax |
| 14 | Rico Dowdle | Dal vs Cin |
| 15 | D'Andre Swift (Q) | Chi @ SF |
| 16 | Isaac Guerendo | SF vs Chi |
| 17 | Tyrone Tracy Jr. | NYG vs NO |
| 18 | Chuba Hubbard | Car @ Phi |
| 19 | Isiah Pacheco | KC vs LAC |
| 20 | Rachaad White | TB vs LV |
| Rank | Player | Match |
| 21 | Travis Etienne | Jax @ Ten |
| 22 | Nick Chubb | Cle @ Pit |
| 23 | Braelon Allen | NYJ @ Mia |
| 24 | Jaylen Warren | Pit vs Cle |
| 25 | Gus Edwards | LAC @ KC |
| 26 | Breece Hall (D) | NYJ @ Mia |
| 27 | Jerome Ford | Cle @ Pit |
| 28 | Kareem Hunt | KC vs LAC |
| 29 | Alexander Mattison (Q) | LV @ TB |
| 30 | Tank Bigsby | Jax @ Ten |
| 31 | Tyjae Spears | Ten vs Jax |
| 32 | Devin Singletary | NYG vs NO |
| 33 | Raheem Mostert (Q) | Mia vs NYJ |
| 34 | Jonathon Brooks | Car @ Phi |
| 35 | Zach Charbonnet | Sea @ Ari |
| 36 | Isaiah Davis | NYJ @ Mia |
| 37 | Ameer Abdullah | LV @ TB |
| 38 | Cam Akers | Min vs Atl |
| 39 | Ray Davis | Buf @ LAR |
| 40 | Sincere McCormick | LV @ TB |
