All position ranks are: QB RB WR TE FLEX DEF
These rankings were updated as of Sat 9:45 AM ET.
| Rank | Player | Match |
| 1 | Ja'Marr Chase | Cin @ LAC |
| 2 | Amon-Ra St. Brown | Det vs Jax |
| 3 | Nico Collins (P) | Hou @ Dal |
| 4 | Justin Jefferson | Min @ Ten |
| 5 | Garrett Wilson | NYJ vs Ind |
| 6 | Tyreek Hill | Mia vs LV |
| 7 | Davante Adams (Q) | NYJ vs Ind |
| 8 | CeeDee Lamb | Dal vs Hou |
| 9 | Cooper Kupp | LAR @ NE |
| 10 | George Pickens | Pit vs Bal |
| 11 | Puka Nacua | LAR @ NE |
| 12 | Drake London | Atl @ Den |
| 13 | Deebo Samuel | SF vs Sea |
| 14 | DK Metcalf | Sea @ SF |
| 15 | Zay Flowers | Bal @ Pit |
| 16 | Tee Higgins | Cin @ LAC |
| 17 | Courtland Sutton | Den vs Atl |
| 18 | Ladd McConkey | LAC vs Cin |
| 19 | Tank Dell | Hou @ Dal |
| 20 | Jayden Reed | GB @ Chi |
| 21 | Khalil Shakir | Buf vs KC |
| 22 | Cedric Tillman | Cle vs Pit |
| 23 | Jauan Jennings | SF vs Sea |
| 24 | Jakobi Meyers | LV @ Mia |
| 25 | Darnell Mooney | Atl @ Den |
| Rank | Player | Match |
| 26 | Calvin Ridley | Ten vs Min |
| 27 | Jaxon Smith-Njigba | Sea @ SF |
| 28 | DeAndre Hopkins | KC @ Buf |
| 29 | Brian Thomas Jr. | Jax @ Det |
| 30 | Jameson Williams | Det vs Jax |
| 31 | DJ Moore | Chi vs GB |
| 32 | Jaylen Waddle | Mia vs LV |
| 33 | Quentin Johnston | LAC vs Cin |
| 34 | Josh Downs | Ind @ NYJ |
| 35 | Jerry Jeudy | Cle vs Pit |
| 36 | Romeo Doubs | GB @ Chi |
| 37 | Amari Cooper (Q) | Buf vs KC |
| 38 | Tyler Lockett | Sea @ SF |
| 39 | Keenan Allen | Chi vs GB |
| 40 | DeMario Douglas | NE vs LAR |
| 41 | Jordan Addison | Min @ Ten |
| 42 | Rashod Bateman | Bal @ Pit |
| 43 | Rome Odunze | Chi vs GB |
| 44 | Elijah Moore | Cle vs Pit |
| 45 | Christian Watson | GB @ Chi |
| 46 | Michael Pittman Jr. | Ind @ NYJ |
| 47 | Joshua Palmer | LAC vs Cin |
| 48 | Xavier Worthy | KC @ Buf |
| 49 | Ricky Pearsall | SF vs Sea |
| 50 | Demarcus Robinson | LAR @ NE |
