Other position ranks are: QB | RB |WR |TE |FLEX | D
These rankings were updated as of Sun 9:30 AM ET.
| Rank | Player | Match |
| 1 | Saquon Barkley | NYG @ Dal |
| 2 | Alvin Kamara | NO vs Hou |
| 3 | Christian McCaffrey | Car vs LAR |
| 4 | Ezekiel Elliott | Dal vs NYG |
| 5 | David Johnson | Ari vs Det |
| 6 | Dalvin Cook | Min vs Atl |
| 7 | Nick Chubb | Cle vs Ten |
| 8 | Le'Veon Bell | NYJ vs Buf |
| 9 | Chris Carson | Sea vs Cin |
| 10 | Leonard Fournette | Jax vs KC |
| 11 | James Conner | Pit @ NE |
| 12 | Kerryon Johnson | Det @ Ari |
| 13 | Todd Gurley | LAR @ Car |
| 14 | Joe Mixon | Cin @ Sea |
| 15 | Austin Ekeler | LAC vs Ind |
| 16 | Devonta Freeman | Atl @ Min |
| 17 | Damien Williams | KC @ Jax |
| 18 | Derrick Henry | Ten @ Cle |
| 19 | Mark Ingram | Bal @ Mia |
| 20 | Josh Jacobs | Oak vs Den |
| Rank | Player | Match |
| 21 | Duke Johnson | Hou @ NO |
| 22 | Phillip Lindsay | Den @ Oak |
| 23 | Marlon Mack | Ind @ LAC |
| 24 | Sony Michel | NE vs Pit |
| 25 | Tevin Coleman | SF @ TB |
| 26 | James White | NE vs Pit |
| 27 | Matt Breida | SF @ TB |
| 28 | Derrius Guice | Wsh @ Phi |
| 29 | Kenyan Drake | Mia vs Bal |
| 30 | Latavius Murray | NO vs Hou |
| 31 | Rashaad Penny | Sea vs Cin |
| 32 | Justin Jackson | LAC vs Ind |
| 33 | Peyton Barber | TB vs SF |
| 34 | Miles Sanders | Phi vs Wsh |
| 35 | Jordan Howard | Phi vs Wsh |
| 36 | Devin Singletary | Buf @ NYJ |
| 37 | Jalen Richard | Oak vs Den |
| 38 | Dion Lewis | Ten @ Cle |
| 39 | Royce Freeman | Den @ Oak |
| 40 | Kalen Ballage | Mia vs Bal |
