All position ranks are: QB RB WR TE FLEX DEF
These rankings were updated as of Sat 9:56 AM ET.
| Rank | Player | Match |
| 1 | Jahmyr Gibbs | Det @ Car |
| 2 | Jonathan Taylor | Ind @ Wsh |
| 3 | Bijan Robinson | Atl @ NO |
| 4 | Jaxon Smith-Njigba | Sea vs LAC |
| 5 | Derrick Henry | Bal vs Ten |
| 6 | Christian McCaffrey | SF vs Den |
| 7 | Kenneth Walker III | KC @ LV |
| 8 | Amon-Ra St. Brown | Det @ Car |
| 9 | Ja'Marr Chase | Cin vs Jax |
| 10 | Puka Nacua | LAR @ Phi |
| 11 | James Cook | Buf vs NE |
| 12 | Chris Olave | NO vs Atl |
| 13 | Chase Brown | Cin vs Jax |
| 14 | Ashton Jeanty | LV vs KC |
| 15 | Chuba Hubbard | Car vs Det |
| 16 | Jeremiyah Love | Ari @ NYG |
| 17 | Zay Flowers (Q) | Bal vs Ten |
| 18 | Aaron Jones | Min vs Mia |
| 19 | CeeDee Lamb | Dal @ Hou |
| 20 | Drake London | Atl @ NO |
| 21 | Cam Skattebo | NYG vs Ari |
| 22 | Trey McBride | Ari @ NYG |
| 23 | Kyren Williams | LAR @ Phi |
| 24 | Saquon Barkley | Phi vs LAR |
| 25 | Brock Bowers | LV vs KC |
| 26 | Christian Watson | GB @ TB |
| 27 | D'Andre Swift | Chi vs NYJ |
| 28 | Parker Washington | Jax @ Cin |
| 29 | Garrett Wilson | NYJ @ Chi |
| 30 | Tee Higgins | Cin vs Jax |
| 31 | Nico Collins | Hou vs Dal |
| 32 | Davante Adams | LAR @ Phi |
| 33 | Javonte Williams | Dal @ Hou |
| 34 | Bucky Irving | TB vs GB |
| 35 | Bhayshul Tuten | Jax @ Cin |
| Rank | Player | Match |
| 36 | George Pickens | Dal @ Hou |
| 37 | David Montgomery | Hou vs Dal |
| 38 | Rashee Rice | KC @ LV |
| 39 | George Kittle | SF vs Den |
| 40 | Tetairoa McMillan | Car vs Det |
| 41 | Braelon Allen | NYJ @ Chi |
| 42 | Josh Downs | Ind @ Wsh |
| 43 | Jordan Addison | Min vs Mia |
| 44 | Jacory Croskey-Merritt | Wsh vs Ind |
| 45 | Tyler Warren | Ind @ Wsh |
| 46 | Michael Wilson | Ari @ NYG |
| 47 | Terry McLaurin (Q) | Wsh vs Ind |
| 48 | Malik Nabers | NYG vs Ari |
| 49 | Dalton Kincaid | Buf vs NE |
| 50 | Travis Kelce | KC @ LV |
| 51 | Jaylen Waddle | Den @ SF |
| 52 | D.J. Moore | Buf vs NE |
| 53 | Omarion Hampton | LAC @ Sea |
| 54 | Jalen Coker (Q) | Car vs Det |
| 55 | J.K. Dobbins | Den @ SF |
| 56 | Tony Pollard | Ten @ Bal |
| 57 | Matthew Golden | GB @ TB |
| 58 | Isaiah Likely | NYG vs Ari |
| 59 | Ladd McConkey (Q) | LAC @ Sea |
| 60 | Trayveon Williams | Det @ Car |
| 61 | Stefon Diggs | Wsh vs Ind |
| 62 | Sam LaPorta | Det @ Car |
| 63 | TreVeyon Henderson | NE @ Buf |
| 64 | Mark Andrews | Bal vs Ten |
| 65 | Rhamondre Stevenson | NE @ Buf |
| 66 | Alvin Kamara | NO vs Atl |
| 67 | Mike Evans (Q) | SF vs Den |
| 68 | Tucker Kraft | GB @ TB |
| 69 | Deebo Samuel | SF vs Den |
| 70 | Emeka Egbuka | TB vs GB |
