All position ranks are: QB RB WR TE FLEX DEF
These rankings were updated as of Sat 9:56 AM ET.
| Rank | Player | Match |
| 1 | Jahmyr Gibbs | Det @ Car |
| 2 | Jonathan Taylor | Ind @ Wsh |
| 3 | Bijan Robinson | Atl @ NO |
| 4 | Derrick Henry | Bal vs Ten |
| 5 | Christian McCaffrey | SF vs Den |
| 6 | Kenneth Walker III | KC @ LV |
| 7 | James Cook | Buf vs NE |
| 8 | Chase Brown | Cin vs Jax |
| 9 | Ashton Jeanty | LV vs KC |
| 10 | Chuba Hubbard | Car vs Det |
| 11 | Jeremiyah Love | Ari @ NYG |
| 12 | Aaron Jones | Min vs Mia |
| 13 | Cam Skattebo | NYG vs Ari |
| 14 | Kyren Williams | LAR @ Phi |
| 15 | Saquon Barkley | Phi vs LAR |
| 16 | D'Andre Swift | Chi vs NYJ |
| 17 | Javonte Williams | Dal @ Hou |
| 18 | Bucky Irving | TB vs GB |
| 19 | Bhayshul Tuten | Jax @ Cin |
| 20 | David Montgomery | Hou vs Dal |
| Rank | Player | Match |
| 21 | Braelon Allen | NYJ @ Chi |
| 22 | Jacory Croskey-Merritt | Wsh vs Ind |
| 23 | Omarion Hampton | LAC @ Sea |
| 24 | J.K. Dobbins | Den @ SF |
| 25 | Tony Pollard | Ten @ Bal |
| 26 | TreVeyon Henderson | NE @ Buf |
| 27 | Rhamondre Stevenson | NE @ Buf |
| 28 | Alvin Kamara | NO vs Atl |
| 29 | Kyle Monangai | Chi vs NYJ |
| 30 | MarShawn Lloyd | GB @ TB |
| 31 | RJ Harvey | Den @ SF |
| 32 | Emanuel Wilson | Sea vs LAC |
| 33 | Woody Marks | Hou vs Dal |
| 34 | Kenneth Gainwell | TB vs GB |
| 35 | Tyler Allgeier | Ari @ NYG |
| 36 | Blake Corum | LAR @ Phi |
| 37 | George Holani | Sea vs LAC |
| 38 | Chris Rodriguez Jr. | Jax @ Cin |
| 39 | Tyjae Spears (Q) | Ten @ Bal |
| 40 | Ollie Gordon | Mia @ Min |
