All position ranks are: QB RB WR TE FLEX DEF
These rankings were updated as of Thu 2:00 PM ET.
| Rank | Player | Match |
| 1 | Tyreek Hill | Mia vs NYG |
| 2 | Justin Jefferson | Min vs KC |
| 3 | Ja'Marr Chase | Cin @ Ari |
| 4 | A.J. Brown | Phi @ LAR |
| 5 | Amon-Ra St. Brown (GTD) | Det vs Car |
| 6 | Puka Nacua | LAR vs Phi |
| 7 | Jaylen Waddle | Mia vs NYG |
| 8 | DeVonta Smith | Phi @ LAR |
| 9 | Nico Collins | Hou @ Atl |
| 10 | Chris Olave | NO @ NE |
| 11 | Garrett Wilson | NYJ @ Den |
| 12 | Marquise Brown | Ari vs Cin |
| 13 | Michael Pittman Jr. | Ind vs Ten |
| 14 | DeAndre Hopkins | Ten @ Ind |
| 15 | Cooper Kupp | LAR vs Phi |
| 16 | Zay Flowers | Bal @ Pit |
| 17 | Adam Thielen | Car @ Det |
| 18 | George Pickens | Pit vs Bal |
| 19 | Jerry Jeudy (GTD) | Den vs NYJ |
| 20 | Tank Dell | Hou @ Atl |
| 21 | Tutu Atwell | LAR vs Phi |
| 22 | Courtland Sutton | Den vs NYJ |
| 23 | Michael Thomas | NO @ NE |
| 24 | Jameson Williams | Det vs Car |
| 25 | Drake London | Atl vs Hou |
| Rank | Player | Match |
| 26 | Tyler Boyd | Cin @ Ari |
| 27 | Robert Woods | Hou @ Atl |
| 28 | Jordan Addison | Min vs KC |
| 29 | Allen Lazard | NYJ @ Den |
| 30 | Rashee Rice | KC @ Min |
| 31 | Rondale Moore | Ari vs Cin |
| 32 | Josh Downs | Ind vs Ten |
| 33 | Kendrick Bourne | NE vs NO |
| 34 | Rashid Shaheed | NO @ NE |
| 35 | DJ Chark Jr. | Car @ Det |
| 36 | Wan'Dale Robinson (GTD) | NYG @ Mia |
| 37 | Kadarius Toney | KC @ Min |
| 38 | Michael Wilson | Ari vs Cin |
| 39 | Skyy Moore | KC @ Min |
| 40 | Nick Westbrook-Ikhine | Ten @ Ind |
| 41 | Calvin Austin III | Pit vs Bal |
| 42 | K.J. Osborn | Min vs KC |
| 43 | DeVante Parker | NE vs NO |
| 44 | Marvin Mims | Den vs NYJ |
| 45 | Van Jefferson | LAR vs Phi |
| 46 | Isaiah Hodgins | NYG @ Mia |
| 47 | Odell Beckham Jr. (GTD) | Bal @ Pit |
| 48 | Tyquan Thornton | NE vs NO |
| 49 | JuJu Smith-Schuster | NE vs NO |
| 50 | Parris Campbell | NYG @ Mia |
