All position ranks are: QB RB WR TE FLEX DEF
These rankings were updated as of Thu 12:18 PM ET.
| Rank | Player | Match |
| 1 | Christian McCaffrey | SF vs Ari |
| 2 | Tony Pollard | Dal vs NE |
| 3 | Josh Jacobs | LV @ LAC |
| 4 | Derrick Henry | Ten vs Cin |
| 5 | Bijan Robinson | Atl @ Jax |
| 6 | Travis Etienne | Jax vs Atl |
| 7 | Kenneth Walker III | Sea @ NYG |
| 8 | Devon Achane | Mia @ Buf |
| 9 | Zack Moss | Ind vs LAR |
| 10 | Rhamondre Stevenson | NE @ Dal |
| 11 | Raheem Mostert | Mia @ Buf |
| 12 | Aaron Jones (GTD) | GB vs Det |
| 13 | Miles Sanders (GTD) | Car vs Min |
| 14 | D'Andre Swift | Phi vs Wsh |
| 15 | Kyren Williams | LAR @ Ind |
| 16 | Joe Mixon | Cin @ Ten |
| 17 | Javonte Williams | Den @ Chi |
| 18 | James Conner (GTD) | Ari @ SF |
| 19 | Alvin Kamara | NO vs TB |
| 20 | Alexander Mattison | Min @ Car |
| Rank | Player | Match |
| 21 | Rachaad White | TB @ NO |
| 22 | David Montgomery (GTD) | Det @ GB |
| 23 | Brian Robinson | Wsh @ Phi |
| 24 | Jahmyr Gibbs | Det @ GB |
| 25 | Dameon Pierce | Hou vs Pit |
| 26 | Jerome Ford (GTD) | Cle vs Bal |
| 27 | James Cook | Buf vs Mia |
| 28 | Austin Ekeler (GTD) | LAC vs LV |
| 29 | Najee Harris | Pit @ Hou |
| 30 | Jaylen Warren | Pit @ Hou |
| 31 | Breece Hall (GTD) | NYJ vs KC |
| 32 | Isiah Pacheco | KC @ NYJ |
| 33 | Tyler Allgeier | Atl @ Jax |
| 34 | Matt Breida | NYG vs Sea |
| 35 | Roschon Johnson | Chi vs Den |
| 36 | Joshua Kelley | LAC vs LV |
| 37 | Dalvin Cook | NYJ vs KC |
| 38 | A.J. Dillon | GB vs Det |
| 39 | Khalil Herbert | Chi vs Den |
| 40 | Kenneth Gainwell | Phi vs Wsh |
