All position ranks are: QB RB WR TE FLEX DEF
These rankings were updated as of Sat 12:54 PM ET.
| Rank | Player | Match |
| 1 | Bijan Robinson | Atl vs Chi |
| 2 | Puka Nacua | LAR vs Ari |
| 3 | Jonathan Taylor | Ind vs Ten |
| 4 | Kenneth Walker III | KC vs LAC |
| 5 | Christian McCaffrey | SF vs Wsh |
| 6 | Kyren Williams | LAR vs Ari |
| 7 | Derrick Henry | Bal @ Cle |
| 8 | James Cook | Buf @ LV |
| 9 | CeeDee Lamb | Dal @ GB |
| 10 | Christian Watson | GB vs Dal |
| 11 | Drake London | Atl vs Chi |
| 12 | Chuba Hubbard | Car @ Phi |
| 13 | Jaylen Warren | Pit @ TB |
| 14 | Nico Collins | Hou @ Jax |
| 15 | Mike Evans (Q) | SF vs Wsh |
| 16 | Chris Olave (Q) | NO @ NYG |
| 17 | Javonte Williams | Dal @ GB |
| 18 | Ashton Jeanty | LV vs Buf |
| 19 | Rhamondre Stevenson | NE vs NYJ |
| 20 | Davante Adams | LAR vs Ari |
| 21 | Brock Bowers | LV vs Buf |
| 22 | D'Andre Swift | Chi @ Atl |
| 23 | Trey McBride | Ari @ LAR |
| 24 | George Kittle | SF vs Wsh |
| 25 | Bucky Irving | TB vs Pit |
| 26 | Zay Flowers | Bal @ Cle |
| 27 | A.J. Brown (IR) | NE vs NYJ |
| 28 | George Pickens | Dal @ GB |
| 29 | Cam Skattebo | NYG vs NO |
| 30 | Tyler Warren (Q) | Ind vs Ten |
| 31 | Tetairoa McMillan | Car @ Phi |
| 32 | Garrett Wilson | NYJ @ NE |
| 33 | Parker Washington | Jax vs Hou |
| 34 | Malik Nabers | NYG vs NO |
| 35 | Matthew Golden | GB vs Dal |
| Rank | Player | Match |
| 36 | Bhayshul Tuten | Jax vs Hou |
| 37 | Travis Kelce | KC vs LAC |
| 38 | Woody Marks | Hou @ Jax |
| 39 | Isaiah Likely | NYG vs NO |
| 40 | Tucker Kraft | GB vs Dal |
| 41 | D.K. Metcalf (Q) | Pit @ TB |
| 42 | Tony Pollard | Ten @ Ind |
| 43 | MarShawn Lloyd | GB vs Dal |
| 44 | Jalen Coker | Car @ Phi |
| 45 | Xavier Worthy | KC vs LAC |
| 46 | Luther Burden III | Chi @ Atl |
| 47 | Braelon Allen | NYJ @ NE |
| 48 | Josh Downs | Ind vs Ten |
| 49 | Terry McLaurin (Q) | Wsh @ SF |
| 50 | DeVonta Smith | Phi vs Car |
| 51 | Dameon Pierce | Phi vs Car |
| 52 | Michael Wilson | Ari @ LAR |
| 53 | Emeka Egbuka | TB vs Pit |
| 54 | Dalton Kincaid | Buf @ LV |
| 55 | Alvin Kamara (Q) | NO @ NYG |
| 56 | Quinshon Judkins (Q) | Cle vs Bal |
| 57 | D.J. Moore (Q) | Buf @ LV |
| 58 | Juwan Johnson | NO @ NYG |
| 59 | Denzel Boston | Cle vs Bal |
| 60 | Carnell Tate | Ten @ Ind |
| 61 | Keenan Allen | Ind vs Ten |
| 62 | Devaughn Vele | NO @ NYG |
| 63 | Rome Odunze | Chi @ Atl |
| 64 | Romeo Doubs | NE vs NYJ |
| 65 | Colston Loveland | Chi @ Atl |
| 66 | Khalil Shakir | Buf @ LV |
| 67 | Harold Fannin Jr. | Cle vs Bal |
| 68 | Stefon Diggs (Q) | Wsh @ SF |
| 69 | Tyler Allgeier | Ari @ LAR |
| 70 | Tre Tucker | LV vs Buf |
